Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.53 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.53 |
| ▸ | NOX1 | Q9Y5S8 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | BCHE | P06276 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SNCA | P37840 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901331 | 0.98 | NOX1 (0.55) | NOX1MAPTGAABCHEACHE | |
| SCHEMBL28514723 | 0.95 | NOX1 (0.55) | NOX1MAPTGAABCHEACHE | |
| Boric Acid SCHEMBL28121620 | 0.92 | NOX1 (0.48) | NOX1MAPTGAABCHEACHE | |
| SCHEMBL30274184 | 0.89 | NOX1 (0.67) | NOX1MAPTGAABCHEACHE | |
| SCHEMBL10530491 | 0.89 | NOX1 (0.67) | NOX1MAPTGAABCHEACHE | |
| SCHEMBL29242236 | 0.88 | NOX1 (0.55) | NOX1MAPTGAABCHEACHE | |
| SCHEMBL5123335 | 0.85 | MAPT (0.53) | NOX1MAPTGAABCHEACHE | |
| SCHEMBL21546029 | 0.85 | NOX1 (0.48) | NOX1MAPTGAABCHEACHE | |
| SCHEMBL28255890 | 0.85 | NOX1 (0.48) | NOX1MAPTGAABCHEACHE | |
| SCHEMBL27750897 | 0.85 | NOX1 (0.48) | NOX1MAPTGAABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7794858-B2 | Phenylphenoxazine or phenylphenothiazine- based compound and organic electroluminescent device using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2010-09-14 | — | — | US | claimed |
| US-20090026928-A1 | PHENYLPHENOXAZINE OR PHENYLPHENOTHIAZINE- BASED COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-01-29 | — | — | US | claimed |
| US-7794858-B2 | Phenylphenoxazine or phenylphenothiazine- based compound and organic electroluminescent device using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2010-09-14 | — | — | US | disclosed |
| US-20090026928-A1 | PHENYLPHENOXAZINE OR PHENYLPHENOTHIAZINE- BASED COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090026928-A1 | PHENYLPHENOXAZINE OR PHENYLPHENOTHIAZINE- BASED COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | TYR, MITF, PPOX | ACHE 1286/4885SLC6A2 111/4885SLC6A3 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.