Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748632 | 0.80 | ALDH1A1 (0.50) | ALDH1A1SSTR5FAAHDRD2DRD4 | |
| SCHEMBL2953829 | 0.73 | MCHR1 (0.71) | ALDH1A1DRD4LMNA | |
| SCHEMBL1748105 | 0.71 | SSTR5 (0.48) | ALDH1A1SSTR5KMT2A | |
| SCHEMBL3782674 | 0.71 | SSTR5 (0.60) | ALDH1A1SSTR5FAAHDRD2DRD4 | |
| SCHEMBL28775007 | 0.70 | FAAH (0.49) | ALDH1A1SSTR5FAAHDRD2DRD4 | |
| SCHEMBL3782984 | 0.70 | SSTR5 (0.59) | ALDH1A1SSTR5 | |
| SCHEMBL1877830 | 0.70 | SSTR5 (0.57) | ALDH1A1SSTR5FAAH | |
| SCHEMBL2951445 | 0.70 | MCHR1 (0.55) | ALDH1A1DRD4KMT2A | |
| SCHEMBL27733028 | 0.69 | SSTR5 (0.48) | ALDH1A1SSTR5FAAHDRD2DRD4 | |
| SCHEMBL3771840 | 0.69 | SSTR5 (0.58) | ALDH1A1SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479257-A | Pyrimidine and quinazoline derivatives | HOFFMANN LA ROCHE (CH) | 2009-07-08 | — | — | CN | disclosed |