Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16462683 | 0.83 | GAA (0.53) | CYP2D6CHRNA7KMT2AMAPTGAA | |
| SCHEMBL4113163 | 0.81 | DRD2 (0.51) | HSP90AA1HSP90AB1MAPTGAARAD52 | |
| SCHEMBL1813597 | 0.80 | CHRNA7 (0.40) | CYP2D6CHRNA7MEN1CYP2C19KMT2A | |
| SCHEMBL2481239 | 0.80 | DRD2 (0.49) | KMT2AMAPTGAARAD52GFER | |
| SCHEMBL10756068 | 0.80 | DRD4 (0.60) | DRD2DRD3KDM4E | |
| SCHEMBL6200811 | 0.79 | CHRNA7 (0.42) | CYP2D6CHRNA7MEN1CYP2C19KMT2A | |
| SCHEMBL18039581 | 0.78 | CHRM4 (0.39) | CHRNA7MAPTGAARAD52GFER | |
| SCHEMBL4880816 | 0.78 | ALDH1A1 (0.44) | MEN1CYP2C19KMT2ACYP2C9MAPT | |
| SCHEMBL1897597 | 0.77 | ALDH1A1 (0.47) | MEN1CYP2C19KMT2ACYP2C9MAPT | |
| SCHEMBL4430996 | 0.77 | ALDH1A1 (0.47) | MEN1CYP2C19KMT2ACYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102796099-A | Imidazoquinolines as lipid kinase inhibitors | NOVARTIS AG | 2012-11-28 | — | — | CN | disclosed |
| CN-101495477-A | Imidazoquinolines as lipid kinase inhibitors | NOVARTIS AG (CH) | 2009-07-29 | — | — | CN | disclosed |