Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3657467 | 0.84 | PGR (0.50) | SMN1; SMN2HIF1ASLC6A2TAAR1PPARG | |
| SCHEMBL419615 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2HIF1ASLC6A2TAAR1PPARG | |
| SCHEMBL7908766 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2HIF1ASLC6A2TAAR1PPARG | |
| SCHEMBL7908936 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2HIF1ASLC6A2TAAR1PPARG | |
| SCHEMBL687447 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2HIF1ASLC6A2TAAR1PPARG | |
| SCHEMBL3730337 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1ASLC6A2TAAR1PPARG | |
| SCHEMBL10825185 | 0.78 | HIF1A (0.48) | SMN1; SMN2HIF1ASLC6A2TAAR1PPARG | |
| SCHEMBL10029155 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2HIF1ASLC6A2TAAR1PPARG | |
| SCHEMBL7300860 | 0.77 | SLC13A5 (0.56) | SMN1; SMN2HIF1AFDPSCYP2C9CYP2C19 | |
| SCHEMBL27639696 | 0.77 | SMN1; SMN2 (0.62) | SMN1; SMN2HIF1ASLC6A2TAAR1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101878026-B | Pharmacological adjunctive therapy associated with glaucoma filtration surgery | BAUSCH & LOMB | 2013-11-20 | — | — | CN | disclosed |
| CN-101484187-B | Composition comprising dissociated glucocorticoid receptor agonist and immunosuppressant for treating dry eye | BAUSCH & LOMB INCORPROATED | 2012-12-26 | — | — | CN | disclosed |
| CN-101553214-B | Compositions and methods for treating, controlling, reducing, ameliorating, or preventing allergy | BAUSCH & LOMB INCORPROATED | 2012-12-26 | — | — | CN | disclosed |
| CN-101969950-A | Compositions comprising a dissociated glucocorticoid receptor agonist for treating or controlling anterior-segment inflammation | BAUSCH & LOMB | 2011-02-09 | — | — | CN | disclosed |
| CN-101878026-A | Pharmacological adjunctive therapy associated with glaucoma filtration surgery | BAUSCH & LOMB | 2010-11-03 | — | — | CN | disclosed |
| CN-101553214-A | Compositions and methods for treating, controlling, reducing, ameliorating, or preventing allergy | BAUSCH & LOMB (US) | 2009-10-07 | — | — | CN | disclosed |
| CN-101528208-A | Compositions and methods for treating or preventing glaucoma or its progression | BAUSCH & LOMB (US) | 2009-09-09 | — | — | CN | disclosed |
| CN-101522187-A | Compositions and methods for treating, reducing, ameliorating, or alleviating posterior-segment ophthalmic diseases | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101522196-A | Treatment of infections and their sequelae with combined isolated glucocorticoid receptor agonists and anti-infective agents | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101484187-A | Composition comprising dissociated glucocorticoid receptor agonist and immunosuppressant for treating dry eye | BAUCH & LOMB INC (US) | 2009-07-15 | — | — | CN | disclosed |