Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827950 | 0.83 | IGF1R (0.48) | TAAR1HPGDHRH3 | |
| SCHEMBL692205 | 0.83 | ESR1 (0.53) | TAAR1ALDH1A1HSD17B10ESR1ADRA2A | |
| SCHEMBL31277094 | 0.83 | TAAR1 (0.48) | TAAR1ALDH1A1HSD17B10ESR1ADRA2A | |
| SCHEMBL11540618 | 0.82 | TRPA1 (0.44) | TAAR1PTGS1PTGS2 | |
| SCHEMBL7056724 | 0.82 | MAOB (0.50) | ALDH1A1CYP3A4HRH3 | |
| SCHEMBL2571201 | 0.81 | CYP2D6 (0.49) | HPGDSLC6A3LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL10472566 | 0.81 | CYP2D6 (0.49) | HPGDSLC6A3LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL560468 | 0.81 | CYP2D6 (0.49) | HPGDSLC6A3LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8716205 | 0.80 | RARB (0.57) | ALDH1A1HSD17B10ESR1ADRA2AADORA3 | |
| SCHEMBL12888466 | 0.79 | CALM1 (0.59) | TAAR1ALDH1A1SLC6A4KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484187-A | Composition comprising dissociated glucocorticoid receptor agonist and immunosuppressant for treating dry eye | BAUCH & LOMB INC (US) | 2009-07-15 | — | — | CN | disclosed |