SCHEMBL27769845

SCHEMBL27769845

NC[P](=O)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
LOXL2 Q9Y4K0 2/20 0.38
TAAR1 Q96RJ0 6/20 0.35
HTR2A P28223 2/20 0.35
CYP2A6 P11509 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP1A2 P05177 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
TRPM2 O94759 1/20 0.32
ALDH1A1 P00352 1/20 0.32
THRB P10828 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
ALOX12 P18054 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
ESR1 P03372 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL27502958 0.89 LMNA (0.46) CYP3A4TDP1LOXL2TAAR1CYP2A6
SCHEMBL27587243 0.76 TDP1 (0.43) CYP3A4TDP1ALDH1A1HPGDTSHR
SCHEMBL2155208 0.74 CYP3A4 (0.41) CYP3A4TDP1CYP1A2KDM4EMEN1
SCHEMBL28501854 0.73 MAOA (0.42) HTR2AHRH1MAOA
SCHEMBL2329641 0.72 CYP3A4 (0.45) CYP3A4TDP1LOXL2TAAR1HTR2A
SCHEMBL28443365 0.72 TSHR (0.40) CYP3A4TDP1LOXL2ALDH1A1HPGD
SCHEMBL27897907 0.70 CYP3A4 (0.43) CYP3A4TDP1LOXL2TAAR1HTR2A
SCHEMBL27822953 0.70 AKR1B1 (0.41) CYP3A4TDP1SMN1; SMN2KDM4EMEN1
SCHEMBL5572991 0.70 TDP1 (0.38) CYP3A4TDP1SMN1; SMN2KDM4EMEN1
SCHEMBL28050880 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103275124-B A kind of Alkyl phosphine oxide silane coupling agent and preparation method thereof TSINGHUA UNIVERSITY (CN) 2016-02-10 CN claimed
CN-110462867-A Organic electroluminescent device KONICA MINOLTA INC 2019-11-15 CN disclosed
CN-109315046-A The manufacturing method and organic electroluminescent device of organic electroluminescent device 柯尼卡美能达株式会社 2019-02-05 CN disclosed
CN-108369995-A Organic electroluminescent device, the manufacturing method of organic electroluminescent device, display device, lighting device and organic electroluminescent device material 柯尼卡美能达株式会社 2018-08-03 CN disclosed
CN-108026122-A The method for preparing phosphorous cyanhydrin ester 拜耳作物科学股份公司 2018-05-11 CN disclosed
CN-107922447-A The method for preparing phosphorous cyanhydrin ester 拜耳作物科学股份公司 2018-04-17 CN disclosed
CN-106459110-A Process for preparing phosphorus-containing cyanohydrins 拜耳作物科学股份公司 2017-02-22 CN disclosed
CN-103259044-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEMICAL CORP. (JP) 2016-02-10 CN disclosed
CN-103275124-B A kind of Alkyl phosphine oxide silane coupling agent and preparation method thereof TSINGHUA UNIVERSITY (CN) 2016-02-10 CN disclosed
CN-102097654-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEMICAL CORP. (JP) 2014-10-01 CN disclosed
CN-103275124-A Alkyl phosphine oxide silane coupling agent and preparation method UNIV TSINGHUA 2013-09-04 CN disclosed
CN-103259044-A Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEM CORP 2013-08-21 CN disclosed
CN-101432923-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEM CORP 2012-04-18 CN disclosed
CN-102097654-A Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEM CORP 2011-06-15 CN disclosed
CN-101432923-A Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery MITSUBISHI CHEM CORP (JP) 2009-05-13 CN disclosed