Phthalic Acid

Phthalic Acid

SCHEMBL2777

CC(=O)O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 known ✓ P03372 1/20 0.58
ALDH1A1 P00352 5/20 0.82
ALOX15 P16050 1/20 0.82
AKR1C3 P42330 2/20 0.61
CA12 O43570 3/20 0.60
CA1 P00915 3/20 0.60
CA2 P00918 3/20 0.60
CA4 P22748 3/20 0.60
CA7 P43166 3/20 0.60
CA9 Q16790 3/20 0.60
KDM4E B2RXH2 2/20 0.59
HMGB1 P09429 2/20 0.59
HPGD P15428 2/20 0.59
NAPRT Q6XQN6 2/20 0.59
CA6 P23280 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CA14 Q9ULX7 1/20 0.59
HSD17B10 Q99714 2/20 0.58
ITGB3 P05106 1/20 0.58
ITGA2B P08514 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL27618507 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL2561870 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL30100313 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL8398555 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL7897915 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL11323294 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL29358471 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL6336453 0.97 ALDH1A1 (0.78) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL6383293 0.97 ALDH1A1 (0.78) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL1896598 0.97 ALDH1A1 (0.78) ALDH1A1ALOX15AKR1C3CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 96586 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115191-A1 Nilotinib Compositions with Enhanced Solubility NEOFORM BIOPHARMACEUTICAL LTD (CN) 2026-04-30 US claimed
US-12599610-B2 Solid dosage formulations of an orexin receptor antagonist MERCK SHARP & DOHME LLC (US) 2026-04-14 US claimed
US-20260096994-A1 SOLID DISPERSIONS HAVING STABILIZED EMULSION PARTICLES BOEHRINGER INGELHEIM INT (DE) 2026-04-09 US claimed
US-12582629-B1 Extended-release pharmaceutical compositions of Ralinepag INNOVATE THERAPEUTICS LLC (US) 2026-03-24 US claimed
US-20260069544-A1 CENTANAFADINE MULTIPHASIC CONTROLLED-RELEASE PHARMACEUTICAL FORMULATION INNOVATE THERAPEUTICS LLC (US) 2026-03-12 US claimed
US-20260062394-A1 PROCESSES FOR PREPARING OXAZOLIDINONE COMPOUNDS MERCK SHARP & DOHME LLC (US) 2026-03-05 US claimed
EP-4680227-A1 FORMULATIONS OF DANICOPAN AND METHODS OF USE THEREOF Alexion Pharmaceuticals, Inc. (US) 2026-01-21 EP claimed
WO-2025261803-A1 NOVEL GABA-PRODUCING LEVILACTOBACILLUS BREVIS STRAIN AND ITS USE EVONIK OPERATIONS GMBH (DE) 2025-12-26 WO claimed
US-12502358-B1 Centanafadine multiphasic controlled-release pharmaceutical formulation INNOVATE THERAPEUTICS LLC (US) 2025-12-23 US claimed
US-20250375418-A1 1-(NAPHTHALEN-2-YL)-3-AZABICYCLO[3.1.0]HEXANE FOR TREATING MAJOR DEPRESSIVE DISORDER OTSUKA PHARMA CO LTD (JP) 2025-12-11 US claimed
US-3997346-A Method for stabilizing the image of a thermally developable photosensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-12-14 US claimed
US-3981984-A Color film coating of tablets and the like COLORCON INCORPORATED (US) 1976-09-21 US claimed
US-3965260-A Anti-inflammatory dipeptide McArthur, John N. (CA) 1976-06-22 US claimed
US-3961041-A PARKINSON'S DISEASE INTERX RESEARCH CORPORATION (US) 1976-06-01 US claimed
US-3957523-A CELLULOSE DERIVATIVES SHINETSU CHEMICAL COMPANY (JA) 1976-05-18 US claimed
US-3953360-A DISPERSION OF ACTIVATED CHARCOAL IN POLYMER MATRIX TOYO JOZO COMPANY, LTD. (JA) 1976-04-27 US claimed
US-3951859-A Molecular sieving particle and preparation thereof TOYO JOZO CO., LTD. (JA) 1976-04-20 US claimed
US-3943063-A Preparation of microcapsules TOYO JOZO COMPANY, LTD. (JA) 1976-03-09 US claimed
US-3937798-A METHOD OF CONTROLLING HYDROGEN ION CONCENTRATION BY MICROCAPSULES FUJI PHOTO FILM CO., LTD. (JA) 1976-02-10 US claimed
US-3933508-A ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, BINDER FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US claimed