Phthalic Acid

Phthalic Acid

SCHEMBL8398555

CC(=O)O.CC(=O)O.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 known ✓ P03372 1/20 0.58
ALDH1A1 P00352 5/20 0.82
ALOX15 P16050 1/20 0.82
AKR1C3 P42330 2/20 0.61
CA12 O43570 3/20 0.60
CA1 P00915 3/20 0.60
CA2 P00918 3/20 0.60
CA4 P22748 3/20 0.60
CA7 P43166 3/20 0.60
CA9 Q16790 3/20 0.60
KDM4E B2RXH2 2/20 0.59
HMGB1 P09429 2/20 0.59
HPGD P15428 2/20 0.59
NAPRT Q6XQN6 2/20 0.59
CA6 P23280 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CA14 Q9ULX7 1/20 0.59
HSD17B10 Q99714 2/20 0.58
ITGB3 P05106 1/20 0.58
ITGA2B P08514 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL2777 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL27618507 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL2561870 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL30100313 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL7897915 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL11323294 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL29358471 1.00 ALDH1A1 (0.82) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL6336453 0.97 ALDH1A1 (0.78) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL6383293 0.97 ALDH1A1 (0.78) ALDH1A1ALOX15AKR1C3CA12CA1
Phthalic Acid SCHEMBL1896598 0.97 ALDH1A1 (0.78) ALDH1A1ALOX15AKR1C3CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2015027-A None JP disclosed
CN-105828806-B Formulations 塞利秘特治疗有限公司 2023-08-29 CN disclosed
US-20230115193-A1 THERMAL TRANSFER SHEET AND METHOD FOR PRODUCING PRINTED MATTER DAI NIPPON PRINTING CO., LTD. (JP) 2023-04-13 US disclosed
CN-101869561-A The improvement release composition that contains tacrolimus LIFECYCLE PHARMA AS 2010-10-27 CN disclosed
CN-1859910-A Modified release composition containing tacrolimus LIFECYCLE PHARMA AS (DK) 2006-11-08 CN disclosed
CN-1083347-C Composition for an ink-jet recording sheet MINNESOTA MINING & MFG (US) 2002-04-24 CN disclosed
EP-0823069-B1 IMAGE-RECORDING ELEMENT POLAROID CORP (US) 1999-06-02 EP disclosed
EP-0808478-B1 DIFFUSION TRANSFER PHOTOGRAPHIC FILM UNIT POLAROID CORP (US) 1998-12-16 EP disclosed
CN-1200083-A Composition for an ink-jet recording sheet MINNESOTA MINING & MFG (US) 1998-11-25 CN disclosed
EP-0823069-A1 IMAGE-RECORDING ELEMENT POLAROID CORPORATION (US) 1998-02-11 EP disclosed
US-5346800-A Stripcoat POLAROID CORPORATION (US) 1994-09-13 US disclosed
US-5214164-A Photographic bleaching, reduction of residue and bleaching times Kubler, Herbert (DE) 1993-05-25 US disclosed
JP-H0215027-A NOVEL PROBUCOL SOLID PREPARATION TAKADA SEIYAKU KK 1990-01-18 JP disclosed
US-4873171-A ADDING A POLYMERIC, WATER PERMEABLE WATER-ABSORBING LAYER BETWEEN TIMING LAYER AND POLYMERIC ACID-REACTING LAYER POLAROID CORPORATION (US) 1989-10-10 US disclosed
US-4563411-A DIFFUSION TRANSFER POLAROID CORPORATION (US) 1986-01-07 US disclosed
US-4424326-A 2-METHYL-5-VINYLPYRIDINE-VINYLBENZYLAMMONIUM SALT COPOLYMER POLAROID CORPORATION (US) 1984-01-03 US disclosed
US-4336322-A DYE RELEASING REDOX COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1982-06-22 US disclosed
US-4322489-A Copolymeric mordants and photographic products and processes utilizing same POLAROID CORPORATION (US) 1982-03-30 US disclosed
US-4009031-A AMMONIA SOLUTION POLAROID CORPORATION (US) 1977-02-22 US disclosed
US-3982946-A Bis-azo pyrazolone type dye developer and light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-09-28 US disclosed