Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27791598 | 1.00 | SLC1A3 (0.37) | SLC1A3SLC1A2SLC1A1MAPTLARS1 | |
| SCHEMBL27791566 | 1.00 | SLC1A3 (0.37) | SLC1A3SLC1A2SLC1A1MAPTLARS1 | |
| SCHEMBL538086 | 0.85 | SLC1A1 (0.45) | SLC1A3SLC1A2SLC1A1LARS1PKM | |
| SCHEMBL3227102 | 0.84 | LARS1 (0.38) | SLC1A3SLC1A2SLC1A1MAPTLARS1 | |
| SCHEMBL27791469 | 0.84 | ALDH1A1 (0.37) | SLC1A3SLC1A2SLC1A1MAPTLARS1 | |
| SCHEMBL27770237 | 0.84 | ALDH1A1 (0.37) | SLC1A3SLC1A2SLC1A1MAPTLARS1 | |
| SCHEMBL3037681 | 0.81 | KMT2A (0.46) | MAPTLARS1ALDH1A1KMT2AHSD11B1 | |
| SCHEMBL27725760 | 0.80 | KMT2A (0.42) | MAPTLARS1ALDH1A1KMT2ACA12 | |
| SCHEMBL27716097 | 0.79 | MAPT (0.41) | MAPTALDH1A1KDM4EKMT2AHSD11B1 | |
| SCHEMBL9728466 | 0.77 | TSHR (0.41) | MAPTALDH1A1KDM4EKMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101641348-B | Imidazolidinone derivatives | HOFFMANN LA ROCHE | 2014-09-10 | — | — | CN | disclosed |
| CN-101641348-A | Imidazolidinone derivatives | HOFFMANN LA ROCHE CH | 2010-02-03 | — | — | CN | disclosed |