Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 7/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | KYNU | Q16719 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.40 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227102 | 0.89 | LARS1 (0.38) | SLC1A1SLC1A3SLC1A2ALPIPKM | |
| SCHEMBL10590019 | 0.86 | ALDH1A1 (0.47) | SLC1A1SLC1A3SLC1A2GRIK1GRIK2 | |
| SCHEMBL27770238 | 0.85 | SLC1A3 (0.37) | SLC1A1SLC1A3SLC1A2PKMLARS1 | |
| SCHEMBL27791566 | 0.85 | SLC1A3 (0.37) | SLC1A1SLC1A3SLC1A2PKMLARS1 | |
| SCHEMBL27791598 | 0.85 | SLC1A3 (0.37) | SLC1A1SLC1A3SLC1A2PKMLARS1 | |
| SCHEMBL27725760 | 0.85 | KMT2A (0.42) | LARS1 | |
| SCHEMBL28335525 | 0.84 | LTA4H (0.44) | SLC1A1SLC1A3SLC1A2ALPIPKM | |
| SCHEMBL27770237 | 0.83 | ALDH1A1 (0.37) | SLC1A1SLC1A3SLC1A2LARS1 | |
| SCHEMBL27791469 | 0.83 | ALDH1A1 (0.37) | SLC1A1SLC1A3SLC1A2LARS1 | |
| SCHEMBL3037681 | 0.80 | KMT2A (0.46) | LARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3242869-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | Cellixbio Private Limited (IN) | 2017-11-15 | — | — | EP | disclosed |
| WO-2016110865-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | CELLIX BIO PRIVATE LIMITED (IN) | 2016-07-14 | — | — | WO | disclosed |
| EP-2414366-A1 | SPIRO DERIVATIVES FOR THE MODULATION OF STEAROYL-COA DESATURASE | Novartis AG (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112520-A1 | SPIRO DERIVATIVES FOR THE MODULATION OF STEAROYL-COA DESATURASE | NOVARTIS AG (CH) | 2010-10-07 | — | — | WO | disclosed |