Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382142 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1AHSD11B1CA1CA2 | |
| SCHEMBL7651608 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1AHSD11B1CA1CA2 | |
| Hydrochloric Acid SCHEMBL382912 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2HIF1AHSD11B1CA1CA2 | |
| SCHEMBL27560670 | 0.84 | PSIP1 (0.44) | SMN1; SMN2HIF1AHSD11B1CA1CA2 | |
| SCHEMBL6341748 | 0.81 | GRM2 (0.47) | SMN1; SMN2HIF1ACA1CA2CA5A | |
| SCHEMBL17541382 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2HIF1AHSD11B1CA1CA2 | |
| SCHEMBL7347935 | 0.76 | CA1 (0.47) | CA1CA2CA9TSHRHTR6 | |
| SCHEMBL27560930 | 0.75 | PSIP1 (0.42) | SMN1; SMN2HSD11B1CA1CA2CA5A | |
| SCHEMBL28026557 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1ACA9CA12KMT2A | |
| SCHEMBL28026558 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1ACA9CA12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101641348-B | Imidazolidinone derivatives | HOFFMANN LA ROCHE | 2014-09-10 | — | — | CN | disclosed |
| CN-101641348-A | Imidazolidinone derivatives | HOFFMANN LA ROCHE CH | 2010-02-03 | — | — | CN | disclosed |