Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026557 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1AKMT2AACHEBCHE | |
| SCHEMBL6544963 | 0.85 | ACHE (0.49) | SMN1; SMN2KMT2AACHEBCHECYP1A2 | |
| SCHEMBL7372959 | 0.83 | ALDH1A1 (0.45) | KMT2AACHEBCHECA12CYP1A2 | |
| SCHEMBL4453723 | 0.79 | CYP3A4 (0.51) | KMT2AACHEBCHECA12CYP1A2 | |
| SCHEMBL29514938 | 0.77 | ALDH1A1 (0.40) | SMN1; SMN2KMT2ACA12CYP3A4CA9 | |
| SCHEMBL27560670 | 0.76 | PSIP1 (0.44) | SMN1; SMN2HIF1AKMT2ACA12CYP1A2 | |
| SCHEMBL382142 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1AKMT2ACA12CA9 | |
| SCHEMBL27770239 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1AKMT2ACA12CA9 | |
| SCHEMBL7651608 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2HIF1AKMT2ACA12CA9 | |
| SCHEMBL5031190 | 0.74 | CYP3A4 (0.46) | SMN1; SMN2KMT2AACHEBCHECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876856-B | A kind of method that Split Method prepares (R) (+) 3 amino piperidine dihydrochloride | 河北凯力昂生物科技有限公司 | 2017-11-21 | — | — | CN | disclosed |
| CN-104829459-B | Splitting method for preparing (R)-(+)-1-naphthyl ethylamine | 河北凯力昂生物科技有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-104876856-A | Method for preparing (R)-(+)-3-piperidinamine dihydrochloride by using resolution method | HEBEI KAILIANG BIOTECHNOLOGY CO LTD | 2015-09-02 | — | — | CN | disclosed |
| CN-104829459-A | Splitting method for preparing (R)-(+)-1-naphthyl ethylamine | HEBEI CHIRAL CHEMISTRY AND BIOTECHNOLOGY CO LTD | 2015-08-12 | — | — | CN | disclosed |