Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770253 | 0.92 | CTSK (0.39) | GAAF2F10PRSS1CTSK | |
| SCHEMBL2386992 | 0.86 | F2 (0.48) | GAAF2F10PRSS1CTSK | |
| SCHEMBL4097703 | 0.86 | F2 (0.48) | GAAF2F10PRSS1CTSK | |
| SCHEMBL2386997 | 0.86 | F2 (0.48) | GAAF2F10PRSS1CTSK | |
| SCHEMBL2456099 | 0.82 | GAA (0.46) | GAAF2F10PRSS1CTSK | |
| SCHEMBL2460778 | 0.82 | GAA (0.46) | GAAF2F10PRSS1CTSK | |
| SCHEMBL5637239 | 0.82 | GAA (0.46) | GAAF2F10PRSS1CTSK | |
| SCHEMBL2456097 | 0.82 | GAA (0.46) | GAAF2F10PRSS1CTSK | |
| SCHEMBL27749157 | 0.81 | IDH1 (0.38) | NAAA | |
| SCHEMBL27628821 | 0.77 | FPR2 (0.43) | GAAF2F10PRSS1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101454313-A | P38 inhibitors and methods of use thereof | ARRAY BIOPHARMA INC (US) | 2009-06-10 | — | — | CN | disclosed |