Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.30 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22397495 | 0.89 | MYC (0.36) | L3MBTL1MYCALDH1A1TSHRGAA | |
| SCHEMBL16671338 | 0.87 | PARP1 (0.36) | MYCTSHRGAASMN1; SMN2TP53 | |
| SCHEMBL28984504 | 0.80 | POLB (0.43) | POLB | |
| SCHEMBL6034220 | 0.80 | GRM5 (0.41) | L3MBTL1ALDH1A1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL27857904 | 0.77 | GAA (0.32) | MYCGAAHTT | |
| SCHEMBL12671549 | 0.75 | SMN1; SMN2 (0.33) | MYCALDH1A1GAASMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL27458213 | 0.75 | GAA (0.30) | GAAHTT | |
| SCHEMBL27303243 | 0.73 | TRIM24 (0.30) | — | |
| SCHEMBL27779336 | 0.73 | GRIA2 (0.31) | ALDH1A1GAAHTT | |
| SCHEMBL27436380 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102417483-A | 2-Phenyl-1H-benzimidazole-4-carboxylate derivatives as PARP inhibitors | UNIV CHINA PHARMA | 2012-04-18 | — | — | CN | disclosed |
| CN-101500997-A | PARP inhibitors | KUDOS PHARM LTD (GB) | 2009-08-05 | — | — | CN | disclosed |