Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27659800 | 0.79 | TDP1 (0.34) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27948302 | 0.77 | TDP1 (0.52) | SMN1; SMN2GAACHRM1POLBALDH1A1 | |
| SCHEMBL10205107 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2GAACHRM1POLBALDH1A1 | |
| SCHEMBL28794684 | 0.75 | TDP1 (0.31) | TDP1 | |
| SCHEMBL27908929 | 0.75 | TDP1 (0.31) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28035538 | 0.73 | TDP1 (0.43) | SMN1; SMN2GAAPOLBALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL27852125 | 0.73 | TDP1 (0.30) | TDP1 | |
| Hydrochloric Acid SCHEMBL27834972 | 0.73 | TDP1 (0.30) | TDP1 | |
| SCHEMBL27909015 | 0.72 | TDP1 (0.32) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28803867 | 0.71 | GPR119 (0.51) | SMN1; SMN2POLBALDH1A1PKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101627029-A | Compounds and compositions as modulators of GPR119 activity | IRM LLC | 2010-01-13 | — | — | CN | disclosed |