Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28794684 | 0.84 | TDP1 (0.31) | TDP1 | |
| Hydrochloric Acid SCHEMBL27852125 | 0.83 | TDP1 (0.30) | TDP1 | |
| Hydrochloric Acid SCHEMBL27834972 | 0.83 | TDP1 (0.30) | TDP1 | |
| SCHEMBL27659800 | 0.78 | TDP1 (0.34) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27660032 | 0.77 | TDP1 (0.45) | TDP1 | |
| SCHEMBL27775941 | 0.75 | CTSK (0.39) | — | |
| SCHEMBL27908929 | 0.74 | TDP1 (0.31) | TDP1 | |
| SCHEMBL27814591 | 0.72 | TDP1 (0.40) | TDP1 | |
| SCHEMBL27660840 | 0.72 | TDP1 (0.40) | TDP1 | |
| SCHEMBL27770659 | 0.72 | SMN1; SMN2 (0.43) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103582638-B | Heteroaryl pyrimidine derivative, preparation method and application thereof | JIANGSU HANSOH PHARMACEUTICAL Co.,Ltd. (CN) | 2016-02-10 | — | — | CN | disclosed |
| CN-102911172-A | Heteroaryl pyrimidine derivatives and preparation method and application thereof | SHANGHAI HENGRUI MEDICINE CO LTD | 2013-02-06 | — | — | CN | disclosed |