Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KAT7 | O95251 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27792052 | 1.00 | MMP1 (0.42) | MMP1MMP9MMP3MMP7GPR119 | |
| SCHEMBL23199280 | 0.89 | NR1H2 (0.47) | MMP1MMP9MMP3MMP7GPR119 | |
| SCHEMBL190647 | 0.89 | NR1H2 (0.47) | MMP1MMP9MMP3MMP7GPR119 | |
| SCHEMBL1088863 | 0.86 | MMP1 (0.43) | MMP1MMP9MMP3MMP7GPR119 | |
| SCHEMBL15771451 | 0.86 | GPR119 (0.41) | MMP1MMP9MMP3MMP7GPR119 | |
| SCHEMBL26537643 | 0.86 | GPR119 (0.41) | MMP1MMP9MMP3MMP7GPR119 | |
| SCHEMBL336963 | 0.86 | GPR119 (0.41) | MMP1MMP9MMP3MMP7GPR119 | |
| SCHEMBL17953649 | 0.86 | NR1H2 (0.42) | MMP1MMP9MMP3MMP7GPR119 | |
| SCHEMBL189851 | 0.85 | MMP1 (0.40) | MMP1MMP9MMP3MMP7GPR119 | |
| SCHEMBL16322162 | 0.84 | MMP1 (0.44) | MMP1MMP9MMP3MMP7GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101600720-A | Phosphoinositide 3-kinase inhibitor compounds and using method | HOFFMANN LA ROCHE (CH) | 2009-12-09 | — | — | CN | disclosed |