Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.34 |
| ▸ | DRD2 | P14416 | 5/20 | 0.31 |
| ▸ | DRD4 | P21917 | 5/20 | 0.31 |
| ▸ | DRD3 | P35462 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850203 | 0.79 | PTGDR2 (0.40) | PTGDR2 | |
| SCHEMBL3159313 | 0.79 | PTGDR2 (0.34) | PTGDR2DRD2DRD4DRD3 | |
| SCHEMBL3166424 | 0.76 | PTGDR2 (0.36) | PTGDR2DRD2DRD4DRD3 | |
| SCHEMBL3165132 | 0.75 | PTGDR2 (0.37) | PTGDR2 | |
| SCHEMBL4419771 | 0.73 | PTGDR2 (0.36) | PTGDR2DRD2DRD4DRD3 | |
| SCHEMBL12678732 | 0.73 | POLB (0.37) | PTGDR2 | |
| SCHEMBL27866952 | 0.71 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL27792913 | 0.71 | PTGDR2 (0.41) | PTGDR2 | |
| SCHEMBL27792893 | 0.60 | PTGDR2 (0.45) | PTGDR2 | |
| SCHEMBL3159412 | 0.60 | PTGDR2 (0.48) | PTGDR2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102442941-A | Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2012-05-09 | — | — | CN | disclosed |
| CN-101636386-A | Polycyclic acid compounds useful as CRTH2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2010-01-27 | — | — | CN | disclosed |