Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | DRD4 | P21917 | 3/20 | 0.31 |
| ▸ | DRD3 | P35462 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3166424 | 0.86 | PTGDR2 (0.36) | PTGDR2DRD2DRD4DRD3 | |
| SCHEMBL3165132 | 0.86 | PTGDR2 (0.37) | PTGDR2 | |
| SCHEMBL12678732 | 0.84 | POLB (0.37) | PTGDR2MAPT | |
| SCHEMBL4415546 | 0.81 | PTGDR2 (0.42) | PTGDR2MAPT | |
| SCHEMBL3159313 | 0.77 | PTGDR2 (0.34) | PTGDR2DRD2DRD4DRD3 | |
| SCHEMBL4413606 | 0.76 | PTGDR2 (0.43) | PTGDR2 | |
| SCHEMBL4419630 | 0.75 | PTGDR2 (0.51) | PTGDR2MAPT | |
| SCHEMBL4414924 | 0.75 | PTGDR2 (0.52) | PTGDR2MAPT | |
| SCHEMBL4418310 | 0.74 | PTPN1 (0.32) | — | |
| SCHEMBL4416672 | 0.74 | PTGDR2 (0.47) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |