Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.59 |
| ▸ | TUBB | P07437 | 3/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.59 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.59 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.59 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.59 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.59 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.59 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.59 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.59 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.59 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.59 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.59 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621478 | 0.86 | KDM4E (0.49) | KMT2AMEN1RAB9ANPC1TUBB4A | |
| SCHEMBL7621487 | 0.86 | KDM4E (0.49) | KMT2AMEN1RAB9ANPC1TUBB4A | |
| SCHEMBL6230731 | 0.84 | KMT2A (0.82) | KMT2AMEN1RAB9ANPC1TUBB4A | |
| SCHEMBL6230728 | 0.84 | KMT2A (0.82) | KMT2AMEN1RAB9ANPC1TUBB4A | |
| SCHEMBL27771778 | 0.82 | KMT2A (0.77) | KMT2AMEN1RAB9ANPC1TUBB4A | |
| SCHEMBL7620399 | 0.76 | NPC1 (0.50) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL7620386 | 0.76 | NPC1 (0.50) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL7621435 | 0.76 | KDM4E (0.51) | KMT2AMEN1RAB9ANPC1TUBB4A | |
| SCHEMBL7621431 | 0.76 | KDM4E (0.51) | KMT2AMEN1RAB9ANPC1TUBB4A | |
| SCHEMBL403796 | 0.75 | PDE5A (0.64) | KMT2AMEN1RAB9AATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101501007-B | Quinazoline derivative | ASKA PARMACEUTICAL CO LTD | 2014-01-29 | — | — | CN | disclosed |
| CN-101501007-A | Quinazoline derivative | ASKA PARMACEUTICAL CO LTD (JP) | 2009-08-05 | — | — | CN | disclosed |