Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.30 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771986 | 0.82 | TLR8 (0.33) | HTR2A | |
| SCHEMBL3091176 | 0.72 | PNP (0.41) | HTR1DHTR1BSLC5A2SLC5A1PNP | |
| SCHEMBL3092049 | 0.71 | SLC5A2 (0.33) | HTR1DHTR1BSLC5A2SLC5A1PNP | |
| SCHEMBL8637440 | 0.71 | IDO1 (0.42) | HTR1DHTR1BSLC5A2SLC5A1PNP | |
| SCHEMBL3074353 | 0.71 | SLC5A2 (0.34) | HTR1DHTR1BSLC5A2SLC5A1PNP | |
| SCHEMBL3093428 | 0.70 | SLC5A2 (0.35) | HTR1DHTR1BSLC5A2SLC5A1PNP | |
| SCHEMBL5544506 | 0.70 | GABRA1 (0.39) | HTR2CHTR2BKCNN2KCNN3 | |
| SCHEMBL24203430 | 0.66 | SLC5A1 (0.42) | HTR1DHTR1BSLC5A2SLC5A1PNP | |
| SCHEMBL3956146 | 0.66 | IDO1 (0.56) | HTR1DHTR1BCOPS5IDO1RAB9A | |
| SCHEMBL2581905 | 0.65 | KEAP1 (0.63) | SLC5A2SLC5A1IDO1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495494-A | Fused ring spiroketal derivative and use thereof as therapeutic agent for diabetes | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2009-07-29 | — | — | CN | disclosed |