Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14256496 | 0.79 | BRD4 (0.42) | BRD4KDM1APRMT5WDR77PDE10A | |
| SCHEMBL10345991 | 0.73 | FDPS (0.44) | BRD4PRMT5WDR77ALDH1A1PDE10A | |
| SCHEMBL6640316 | 0.73 | BRD4 (0.49) | BRD4PRMT5WDR77LMNAPDE10A | |
| SCHEMBL27772029 | 0.71 | BRD4 (0.60) | BRD4MEN1ALDH1A1KMT2ABRDT | |
| SCHEMBL26288716 | 0.70 | MAPK1 (0.46) | MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL7396902 | 0.69 | BRD4 (0.50) | BRD4KDM1AALDH1A1RIPK1 | |
| SCHEMBL14256495 | 0.69 | MAOA (0.49) | MEN1ALDH1A1LMNAKMT2ASLC6A4 | |
| SCHEMBL20237186 | 0.68 | BRD4 (0.52) | BRD4PRMT5WDR77ALDH1A1PDE10A | |
| SCHEMBL12993278 | 0.68 | PDE10A (0.45) | BRD4PDE10ARIPK1SLC6A3SLC6A2 | |
| SCHEMBL29164917 | 0.68 | BRD4 (0.44) | BRD4PRMT5WDR77ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101610813-A | Quinuclidinol derivatives as muscarinic receptor antagonist | ASTRAZENECA AB (SE) | 2009-12-23 | — | — | CN | disclosed |