Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.67 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.67 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.67 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.67 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.67 |
| ▸ | TNKS | O95271 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TTR | P02766 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27792981 | 0.87 | POLH (0.71) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| SCHEMBL2322974 | 0.86 | POLH (1.00) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| SCHEMBL30255788 | 0.86 | POLH (1.00) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| SCHEMBL14917316 | 0.86 | POLH (0.81) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| SCHEMBL20356693 | 0.86 | CYP1B1 (0.76) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| SCHEMBL27793020 | 0.85 | POLH (0.69) | POLH | |
| SCHEMBL27772068 | 0.85 | EGFR (0.76) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| SCHEMBL27792995 | 0.85 | POLH (0.71) | POLH | |
| Luteolin SCHEMBL14917315 | 0.84 | CYP1B1 (0.81) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| SCHEMBL27772065 | 0.83 | POLH (0.76) | POLHKDM4EMEN1SLC22A2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101591319-B | Flavonoid derivatives and application thereof in preparing medicinal composition | FUDAN UNIVERSITY (CN) | 2011-12-21 | — | — | CN | disclosed |
| CN-101591319-A | Flavone derivative and the purposes in pharmaceutical compositions thereof | UNIV FUDAN (CN) | 2009-12-02 | — | — | CN | disclosed |