Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 2/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.75 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.75 |
| ▸ | CA12 | O43570 | 1/20 | 0.75 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.75 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.75 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.75 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.75 |
| ▸ | TNKS | O95271 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | CA2 | P00918 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | TTR | P02766 | 1/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.75 |
| ▸ | APP | P05067 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | GLA | P06280 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30255788 | 0.90 | POLH (1.00) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| SCHEMBL2322974 | 0.90 | POLH (1.00) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| SCHEMBL7072657 | 0.87 | KMT2A (0.71) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| SCHEMBL27772065 | 0.86 | POLH (0.76) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| SCHEMBL27772069 | 0.86 | POLH (0.76) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| SCHEMBL26725168 | 0.86 | POLH (0.76) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| Luteolin SCHEMBL29376494 | 0.86 | POLH (1.00) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| Luteolin SCHEMBL20426 | 0.86 | POLH (1.00) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| Luteolin SCHEMBL29352380 | 0.86 | POLH (1.00) | POLHKDM4EMEN1SLC22A2SLC22A1 | |
| Luteolin SCHEMBL30045580 | 0.86 | POLH (1.00) | POLHKDM4EMEN1SLC22A2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015166041-A1 | FLAVONES AS CYP1A1 INHIBITORS FOR THE TREATMENT OF CANCER | DE MONTFORT UNIVERSITY (GB) | 2015-11-05 | — | — | WO | disclosed |
| US-20130115202-A1 | ANTI-INFLAMMATORY COMPOSITIONS FOR TREATING NEURO-INFLAMMATION | THETA BIOMEDICAL CONSULTING & DEVELOPMENT CO., INC (US) | 2013-05-09 | — | — | US | disclosed |