Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL27773088 | 1.00 | NOD1 (0.49) | NOD1FNTAFNTBFOLH1TLR2 | |
| Phosphoric Acid SCHEMBL27752239 | 1.00 | NOD1 (0.49) | NOD1FNTAFNTBFOLH1TLR2 | |
| Phosphoric Acid SCHEMBL27773103 | 1.00 | NOD1 (0.49) | NOD1FNTAFNTBFOLH1TLR2 | |
| Phosphoric Acid SCHEMBL27773106 | 1.00 | NOD1 (0.49) | NOD1FNTAFNTBFOLH1TLR2 | |
| Phosphoric Acid SCHEMBL27752240 | 1.00 | NOD1 (0.49) | NOD1FNTAFNTBFOLH1TLR2 | |
| SCHEMBL25334014 | 0.95 | NOD1 (0.53) | NOD1FNTAFNTBFOLH1TLR2 | |
| SCHEMBL8664762 | 0.95 | NOD1 (0.53) | NOD1FNTAFNTBFOLH1TLR2 | |
| SCHEMBL8664765 | 0.95 | NOD1 (0.53) | NOD1FNTAFNTBFOLH1TLR2 | |
| SCHEMBL7029218 | 0.95 | NOD1 (0.53) | NOD1FNTAFNTBFOLH1TLR2 | |
| SCHEMBL31078268 | 0.95 | NOD1 (0.53) | NOD1FNTAFNTBFOLH1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101756805-A | N-acyl-lysine conditioning moisturizer | FENGYUN LI | 2010-06-30 | — | — | CN | claimed |
| CN-101505720-B | Gel-like cosmetic | KAO CORP | 2012-09-05 | — | — | CN | disclosed |
| CN-101756805-A | N-acyl-lysine conditioning moisturizer | FENGYUN LI | 2010-06-30 | — | — | CN | disclosed |
| CN-101505720-A | Gel-like cosmetic | KAO CORP (JP) | 2009-08-12 | — | — | CN | disclosed |