Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 9/20 | 0.48 |
| ▸ | ABL1 | P00519 | 8/20 | 0.48 |
| ▸ | BCR | P11274 | 4/20 | 0.48 |
| ▸ | SRC | P12931 | 4/20 | 0.48 |
| ▸ | KIT | P10721 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | FYN | P06241 | 2/20 | 0.48 |
| ▸ | YES1 | P07947 | 2/20 | 0.48 |
| ▸ | LYN | P07948 | 2/20 | 0.48 |
| ▸ | HCK | P08631 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | FGR | P09769 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21495194 | 0.87 | SIK2 (0.48) | FLT3LCKABL1BCRSRC | |
| SCHEMBL4254631 | 0.84 | ABL1 (0.50) | FLT3LCKABL1BCRSRC | |
| SCHEMBL4254834 | 0.81 | LCK (0.52) | FLT3LCKABL1BCRSRC | |
| SCHEMBL22964561 | 0.80 | LCK (0.60) | LCKABL1BCRSRCKIT | |
| SCHEMBL20633817 | 0.79 | RAB9A (0.52) | LCKABL1BCRSRCKIT | |
| SCHEMBL12445981 | 0.79 | LCK (0.52) | FLT3LCKABL1BCRSRC | |
| SCHEMBL22964566 | 0.77 | LCK (0.56) | FLT3LCKABL1BCRSRC | |
| SCHEMBL20785959 | 0.76 | PKMYT1 (0.66) | LCKABL1BCRSRCKIT | |
| SCHEMBL28371011 | 0.76 | LCK (0.63) | LCKABL1BCRSRCKIT | |
| SCHEMBL14141667 | 0.76 | LCK (0.47) | AURKALCKABL1BCRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101597284-A | A kind of preparation method of antineoplastic compound | BEIJING LAIDESAILUSEN PHARMACE (CN) | 2009-12-09 | — | — | CN | disclosed |