Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18324277 | 0.87 | KMT2A (0.56) | KMT2ATDP1MAPTMEN1ALDH1A1 | |
| SCHEMBL9511333 | 0.87 | KMT2A (0.56) | KMT2ATDP1MAPTMEN1ALDH1A1 | |
| SCHEMBL29995417 | 0.87 | KMT2A (0.56) | KMT2ATDP1MAPTMEN1ALDH1A1 | |
| SCHEMBL4216005 | 0.85 | KMT2A (0.54) | KMT2ATDP1MAPTMEN1ALDH1A1 | |
| SCHEMBL28944513 | 0.85 | KMT2A (0.54) | KMT2ATDP1MAPTMEN1ALDH1A1 | |
| SCHEMBL27447227 | 0.85 | LOXL2 (0.55) | KMT2ATDP1MAPTMEN1ALDH1A1 | |
| SCHEMBL27628085 | 0.84 | CYP4F2 (0.58) | KMT2ATDP1MAPTMEN1ALDH1A1 | |
| SCHEMBL1785471 | 0.84 | KMT2A (0.69) | KMT2ATDP1MAPTMEN1ALDH1A1 | |
| SCHEMBL6671241 | 0.81 | KMT2A (0.63) | KMT2ATDP1MAPTMEN1ALDH1A1 | |
| SCHEMBL27648250 | 0.81 | KMT2A (0.50) | KMT2ATDP1MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101501033-B | Compounds having affinity for amyloid | GE HEALTHCARE LTD | 2012-08-01 | — | — | CN | disclosed |
| CN-101918039-B | Use of novel compound having affinity for amyloid, and process for production of the same | NIHON MEDIPHYSICS CO LTD | 2012-01-04 | — | — | CN | disclosed |
| CN-101918039-A | Use of novel compound having affinity for amyloid, and process for production of the same | NIHON MEDIPHYSICS CO LTD | 2010-12-15 | — | — | CN | disclosed |
| CN-101501033-A | Novel compound having affinity for amyloid | NIHON MEDIPHYSICS CO LTD (JP) | 2009-08-05 | — | — | CN | disclosed |