⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277523 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL1717671 | 0.72 | TSHR (0.39) | — | |
| SCHEMBL276087 | 0.69 | — | — | |
| SCHEMBL12417959 | 0.69 | — | — | |
| SCHEMBL233065 | 0.69 | — | — | |
| SCHEMBL21031025 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL5402885 | 0.67 | TSHR (0.43) | — | |
| SCHEMBL277922 | 0.67 | LMNA (0.46) | — | |
| SCHEMBL23567445 | 0.67 | — | — | |
| SCHEMBL7870996 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134013-B2 | Amide compound and thrombopoietin receptor activator | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-03-13 | — | — | US | disclosed |
| US-20100310536-A1 | METHOD FOR EXPANDING HEMATOPOIETIC STEM CELLS USING HETEROCYCLIC COMPOUND | NISSAN CHEMICAL INDUSTRIES LIMITED (JP) | 2010-12-09 | — | — | US | disclosed |
| EP-2228435-A1 | METHOD FOR AMPLIFICATION OF HEMATOPOIETIC STEM CELL USING HETEROCYCLIC COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2010-09-15 | — | — | EP | disclosed |
| US-20090131659-A1 | AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
| EP-1845090-A1 | AMIDE COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR | Nissan Chemical Industries, Ltd. (JP) | 2007-10-17 | — | — | EP | disclosed |
| US-6605631-B1 | Controlling fungi and pests; improved activity and plant tolerability | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-12 | — | — | US | disclosed |
| US-6031110-A | Ortho-substituted 2-methoxyiminophenyl-N-methylacetamides | BASF AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| EP-0668852-B1 | SUBSTITUTED ORTHO-ETHENYL-PHENYL ACETIC ACID DERIVATIVES | BASF AG (DE) | 1998-02-25 | — | — | EP | disclosed |
| US-5633268-A | FUNGICIDES, INSECTICIDES, PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |
| EP-0686152-B1 | ORTHO-SUBSTITUTED 2-METHOXYIMINOPHENYLACETIC ACID METHYLAMIDES | BASF AG (DE) | 1997-05-02 | — | — | EP | disclosed |
| EP-0757042-A1 | Ortho-substituted 2-methoxyiminophenylaceticacid methylester | BASF Aktiengesellschaft (DE) | 1997-02-05 | — | — | EP | disclosed |
| EP-0686152-A1 | ORTHO-SUBSTITUTED 2-METHOXYIMINOPHENYLACETIC ACID METHYLAMIDES | BASF AG (DE) | 1995-12-13 | — | — | EP | disclosed |
| EP-0668852-A1 | SUBSTITUTED ORTHO-ETHENYL-PHENYL ACETIC ACID DERIVATIVES | BASF Aktiengesellschaft (DE) | 1995-08-30 | — | — | EP | disclosed |
| WO-1994019331-A1 | ORTHO-SUBSTITUTED 2-METHOXYIMINOPHENYLACETIC ACID METHYLAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1994-09-01 | — | — | WO | disclosed |
| WO-1994011334-A1 | SUBSTITUTED ORTHO-ETHENYL-PHENYL ACETIC ACID DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1994-05-26 | — | — | WO | disclosed |
| US-3931331-A | PLANT PROTECTION INTERMEDIATES | ALLIED CHEMICAL CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |