Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | PI4KA | P42356 | 4/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439065 | 0.79 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL28267406 | 0.75 | PDE10A (0.35) | CYP17A1CYP1A2LMNAGLAHSD17B10 | |
| SCHEMBL28057316 | 0.73 | XDH (0.39) | CYP17A1CYP1A2LMNAGLAALDH1A1 | |
| SCHEMBL27816448 | 0.65 | CFTR (0.42) | CFTRCDK1CCNB1CCNE1CDK2 | |
| SCHEMBL9377878 | 0.62 | LMNA (0.45) | CYP17A1CYP1A2LMNAGLAALDH1A1 | |
| SCHEMBL9990572 | 0.62 | MKNK2 (0.40) | CYP17A1CYP1A2LMNAGLAALDH1A1 | |
| SCHEMBL27774843 | 0.61 | METAP1 (0.41) | ALDH1A1TSHRNOS1HSD17B10 | |
| SCHEMBL11807186 | 0.61 | ADORA2A (0.63) | CYP1A2CDK1ALDH1A1TSHRCCNB1 | |
| SCHEMBL5820389 | 0.58 | LMNA (0.42) | LMNAGLAALDH1A1TSHRNOS1 | |
| SCHEMBL1387982 | 0.57 | PDE10A (0.54) | CYP17A1CYP1A2LMNAGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101505762-A | Orally active purinyl inhibitors of heat shock protein 90 | CONFORMA THERAPEUTICS CORP (US) | 2009-08-12 | — | — | CN | disclosed |