Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27775732 | 0.88 | HSD17B10 (0.58) | HSD17B10VCAM1PDK1PDK2PDK3 | |
| SCHEMBL3542314 | 0.86 | HSD17B10 (0.60) | HSD17B10VCAM1PDK1PDK2PDK3 | |
| SCHEMBL1762377 | 0.83 | HSD17B10 (0.56) | HSD17B10VCAM1PDK1PDK2PDK3 | |
| SCHEMBL2816057 | 0.82 | VCAM1 (0.55) | HSD17B10VCAM1PDK1PDK2PDK3 | |
| SCHEMBL7945433 | 0.80 | HSD17B10 (0.62) | HSD17B10VCAM1PDK1PDK2PDK3 | |
| SCHEMBL2813658 | 0.79 | HSD17B10 (0.51) | HSD17B10VCAM1PDK1PDK2PDK3 | |
| SCHEMBL4440258 | 0.79 | HSD17B10 (0.51) | HSD17B10VCAM1PDK1PDK2PDK3 | |
| SCHEMBL1148427 | 0.79 | HSD17B10 (0.60) | HSD17B10VCAM1PDK1PDK2PDK3 | |
| SCHEMBL29563911 | 0.79 | HSD17B10 (0.60) | HSD17B10VCAM1PDK1PDK2PDK3 | |
| SCHEMBL4440253 | 0.78 | KMT2A (0.53) | HSD17B10VCAM1PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679215-A | New benzamide derivatives as the follicle stimulating hormone conditioning agent | ADDEX PHARMA SA | 2010-03-24 | — | — | CN | disclosed |