Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2813658 | 1.00 | HSD17B10 (0.51) | HSD17B10VCAM1KMT2APDK1PDK2 | |
| SCHEMBL2817984 | 0.88 | HSD17B10 (0.51) | HSD17B10VCAM1KMT2APDK1PDK2 | |
| SCHEMBL2816593 | 0.88 | HSD17B10 (0.51) | HSD17B10VCAM1KMT2APDK1PDK2 | |
| SCHEMBL3542314 | 0.82 | HSD17B10 (0.60) | HSD17B10VCAM1KMT2APDK1PDK2 | |
| SCHEMBL27775720 | 0.79 | HSD17B10 (0.56) | HSD17B10VCAM1KMT2APDK1PDK2 | |
| SCHEMBL1762377 | 0.79 | HSD17B10 (0.56) | HSD17B10VCAM1KMT2APDK1PDK2 | |
| SCHEMBL2815063 | 0.78 | ALDH1A1 (0.45) | KMT2AALDH1A1CYP3A4TDP1LMNA | |
| SCHEMBL2816057 | 0.78 | VCAM1 (0.55) | HSD17B10VCAM1KMT2APDK1PDK2 | |
| SCHEMBL8545549 | 0.78 | KMT2A (0.54) | KMT2AALDH1A1CYP3A4TDP1MEN1 | |
| SCHEMBL4440253 | 0.77 | KMT2A (0.53) | HSD17B10VCAM1KMT2APDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134676-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | Addex Pharma SA (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117175-A2 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2008-10-02 | — | — | WO | disclosed |