Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 6/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29629559 | 0.87 | PDE5A (0.44) | GPR6EPHX2PDE4BPDE4APDE4C | |
| SCHEMBL24468016 | 0.87 | PDE5A (0.44) | GPR6EPHX2PDE4BPDE4APDE4C | |
| SCHEMBL3283342 | 0.85 | MAPT (0.45) | EPHX2HRH1CCR3 | |
| SCHEMBL2775449 | 0.85 | GPR119 (0.55) | PDE4BPDE4APDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL2776331 | 0.82 | DPP4 (0.46) | GPR6PDE4B | |
| Hydrochloric Acid SCHEMBL2776335 | 0.82 | DPP4 (0.46) | GPR6PDE4B | |
| Hydrochloric Acid SCHEMBL2779123 | 0.80 | BCL9 (0.43) | GPR6 | |
| SCHEMBL27623158 | 0.80 | PKM (0.47) | — | |
| SCHEMBL23365170 | 0.80 | HRH1 (0.48) | EPHX2HRH1CCR3 | |
| SCHEMBL4682397 | 0.80 | EPHX2 (0.46) | EPHX2RBP4HRH1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |