Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27881007 | 0.84 | KCNH2 (0.42) | KCNH2ALDH1A1PPARAPDPK1HCAR3 | |
| SCHEMBL28331952 | 0.83 | KCNH2 (0.44) | KCNH2ALDH1A1PKMHPGDPPARA | |
| SCHEMBL9535009 | 0.83 | KCNH2 (0.44) | KCNH2ALDH1A1PKMHPGDPPARA | |
| SCHEMBL18857271 | 0.83 | KCNH2 (0.44) | KCNH2ALDH1A1PKMHPGDPPARA | |
| Bromide SCHEMBL28554893 | 0.81 | KCNH2 (0.43) | KCNH2ALDH1A1PKMHPGDPPARA | |
| Bromide SCHEMBL28945697 | 0.81 | KCNH2 (0.43) | KCNH2ALDH1A1PKMHPGDPPARA | |
| Hydrochloric Acid SCHEMBL31146833 | 0.81 | KCNH2 (0.43) | KCNH2ALDH1A1PKMHPGDPPARA | |
| Bromide SCHEMBL31146830 | 0.81 | KCNH2 (0.43) | KCNH2ALDH1A1PKMHPGDPPARA | |
| Hydrochloric Acid SCHEMBL31146835 | 0.81 | KCNH2 (0.43) | KCNH2ALDH1A1PKMHPGDPPARA | |
| SCHEMBL28047511 | 0.79 | KCNH2 (0.35) | KCNH2ALDH1A1HPGDPDPK1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679296-A | Novel 4-phenyl-imidazole-2-thiones used as tyrosinase inhibitors, method for preparing same and use thereof in human medicine and cosmetology | GALDERMA RES & DEV | 2010-03-24 | — | — | CN | disclosed |
| CN-101678000-A | Use of 4-phenyl-imidazole-2-thiones as tyrosinase inhibitors for preparing pharmaceutical or cosmetic compositions for treating or preventing pigment disorders | GALDERMA RES & DEV | 2010-03-24 | — | — | CN | disclosed |