Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535009 | 0.98 | KCNH2 (0.44) | KCNH2HIF1AEPAS1PPARAALDH1A1 | |
| SCHEMBL27775876 | 0.84 | KCNH2 (0.43) | KCNH2PPARAALDH1A1GPR84HCAR2 | |
| SCHEMBL28331952 | 0.81 | KCNH2 (0.44) | KCNH2PPARAALDH1A1LTB4R | |
| SCHEMBL18857271 | 0.81 | KCNH2 (0.44) | KCNH2PPARAALDH1A1LTB4R | |
| Hydrochloric Acid SCHEMBL31146835 | 0.80 | KCNH2 (0.43) | KCNH2PPARAALDH1A1LTB4R | |
| Hydrochloric Acid SCHEMBL31146833 | 0.80 | KCNH2 (0.43) | KCNH2PPARAALDH1A1LTB4R | |
| Bromide SCHEMBL28945697 | 0.80 | KCNH2 (0.43) | KCNH2PPARAALDH1A1LTB4R | |
| Bromide SCHEMBL31146830 | 0.80 | KCNH2 (0.43) | KCNH2PPARAALDH1A1LTB4R | |
| Bromide SCHEMBL28554893 | 0.80 | KCNH2 (0.43) | KCNH2PPARAALDH1A1LTB4R | |
| SCHEMBL28047511 | 0.77 | KCNH2 (0.35) | KCNH2ALDH1A1PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102584709-B | A kind of preparation technology of the Eprosartan intermediate aryl imidazole aldehyde of improvement | 浙江华海药业股份有限公司 | 2016-08-17 | — | — | CN | claimed |
| CN-113372215-B | Novel esterification method for synthesizing p-halomethyl benzoate | 吉林大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-113372215-A | Novel esterification method for synthesizing p-halomethyl benzoate | 吉林大学 | 2021-09-10 | — | — | CN | disclosed |
| CN-107216315-A | Flavones glyoxaline compound and preparation method thereof | 盐城师范学院 | 2017-09-29 | — | — | CN | disclosed |
| CN-102584709-B | A kind of preparation technology of the Eprosartan intermediate aryl imidazole aldehyde of improvement | 浙江华海药业股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-102584709-B | A kind of preparation technology of the Eprosartan intermediate aryl imidazole aldehyde of improvement | 浙江华海药业股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-102584709-B | A kind of preparation technology of the Eprosartan intermediate aryl imidazole aldehyde of improvement | 浙江华海药业股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-102584709-A | Improved process for preparing aryl imidazole aldehyde serving as eprosartan intermediate | ZHEJIANG HUAHAI PHARM CO LTD | 2012-07-18 | — | — | CN | disclosed |
| CN-102584709-A | Improved process for preparing aryl imidazole aldehyde serving as eprosartan intermediate | ZHEJIANG HUAHAI PHARM CO LTD | 2012-07-18 | — | — | CN | disclosed |