Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27881007 | 0.98 | KCNH2 (0.42) | KCNH2HIF1AEPAS1PPARAGPR84 | |
| SCHEMBL18857271 | 0.83 | KCNH2 (0.44) | KCNH2PPARALTB4RALDH1A1PKM | |
| SCHEMBL28331952 | 0.83 | KCNH2 (0.44) | KCNH2PPARALTB4RALDH1A1PKM | |
| SCHEMBL27775876 | 0.83 | KCNH2 (0.43) | KCNH2PPARAGPR84HCAR2ALDH1A1 | |
| Bromide SCHEMBL28945697 | 0.82 | KCNH2 (0.43) | KCNH2PPARALTB4RALDH1A1PKM | |
| Bromide SCHEMBL28554893 | 0.82 | KCNH2 (0.43) | KCNH2PPARALTB4RALDH1A1PKM | |
| Bromide SCHEMBL31146830 | 0.82 | KCNH2 (0.43) | KCNH2PPARALTB4RALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL31146833 | 0.82 | KCNH2 (0.43) | KCNH2PPARALTB4RALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL31146835 | 0.82 | KCNH2 (0.43) | KCNH2PPARALTB4RALDH1A1PKM | |
| SCHEMBL31146832 | 0.78 | KCNH2 (0.40) | KCNH2PPARALTB4RALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528957-A4 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0528957-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-03 | — | — | EP | disclosed |
| WO-1991016889-A1 | FIVE-MEMBERED RING ALKANOIC ACID LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-11-14 | — | — | WO | disclosed |