Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12539828 | 0.83 | CTSK (0.44) | CTSKGAABTKKCNA3EPHX1 | |
| Tert-Butyl Formate SCHEMBL27834962 | 0.80 | GAA (0.39) | CTSKGAABTKKCNA3EPHX1 | |
| SCHEMBL12539827 | 0.78 | CTSK (0.46) | CTSKGAABTKKCNA3EPHX1 | |
| SCHEMBL2074992 | 0.77 | GAA (0.51) | CTSKGAABTKEPHX1CA1 | |
| SCHEMBL12276428 | 0.77 | EPHX1 (0.46) | CTSKGAABTKKCNA3EPHX1 | |
| SCHEMBL13208 | 0.76 | EPHX1 (0.58) | CTSKEPHX1HSD11B1CYP2C9ALDH1A1 | |
| SCHEMBL1780744 | 0.76 | CTSK (0.43) | CTSKGAABTKKCNA3EPHX1 | |
| SCHEMBL3169231 | 0.76 | EPHX2 (0.47) | CTSKGAABTKKCNA3EPHX1 | |
| SCHEMBL27909015 | 0.75 | TDP1 (0.32) | — | |
| SCHEMBL27739847 | 0.74 | KCNA3 (0.46) | CTSKGAABTKKCNA3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101668759-A | [6,5] -bicyclic GPR119G protein-coupled receptor agonists | BRISTOL MYERS SQUIBB CO | 2010-03-10 | — | — | CN | disclosed |