Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25148521 | 0.98 | TSHR (0.42) | TSHRCYP3A4DGKACES2ALDH1A1 | |
| SCHEMBL26740073 | 0.98 | TSHR (0.42) | TSHRCYP3A4DGKACES2ALDH1A1 | |
| SCHEMBL20325479 | 0.98 | TSHR (0.42) | TSHRCYP3A4DGKACES2ALDH1A1 | |
| SCHEMBL18520324 | 0.98 | TSHR (0.42) | TSHRCYP3A4DGKACES2ALDH1A1 | |
| SCHEMBL23469978 | 0.94 | CES2 (0.44) | TSHRDGKACES2MEN1THRB | |
| SCHEMBL27419973 | 0.93 | CES2 (0.47) | DGKACES2MEN1THRBHTT | |
| SCHEMBL21539314 | 0.93 | MEN1 (0.46) | TSHRCYP3A4DGKACES2MEN1 | |
| SCHEMBL4005309 | 0.93 | CES2 (0.47) | DGKACES2MEN1THRBHTT | |
| SCHEMBL21759092 | 0.91 | MEN1 (0.48) | DGKACES2MEN1THRBHTT | |
| SCHEMBL21539334 | 0.91 | MEN1 (0.48) | DGKACES2MEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101511783-A | N-biaryl (hetero) arylsulphonamide derivatives useful in the treatment of diseases mediated by lymphocytes interactions | NOVARTIS AG (CH) | 2009-08-19 | — | — | CN | disclosed |