Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 7/20 | 0.40 |
| ▸ | CES1 | P23141 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4005309 | 1.00 | CES2 (0.47) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL21539334 | 0.98 | MEN1 (0.48) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL21759092 | 0.98 | MEN1 (0.48) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL21539433 | 0.98 | MEN1 (0.48) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL23469978 | 0.98 | CES2 (0.44) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL21539314 | 0.96 | MEN1 (0.46) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL20365468 | 0.93 | DGKA (0.53) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL27775989 | 0.93 | TSHR (0.43) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL18520324 | 0.91 | TSHR (0.42) | CES2MEN1KMT2ATHRBHTT | |
| SCHEMBL25148521 | 0.91 | TSHR (0.42) | CES2MEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112119-A1 | DEGRADER FOR DECOMPOSING CMET PROTEIN, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 이노큐어테라퓨틱스 | 2024-05-30 | — | — | WO | disclosed |