SCHEMBL277761

SCHEMBL277761

Clc1nc2ccccc2[nH]1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.60
NPC1 O15118 8/20 0.60
RAB9A P51151 8/20 0.60
KDM4E B2RXH2 7/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
NPSR1 Q6W5P4 2/20 0.60
PKM P14618 2/20 0.60
ABCB11 O95342 1/20 0.60
TP53 P04637 1/20 0.60
HSD17B10 Q99714 1/20 0.60
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
MASP2 O00187 1/20 0.56
NUDT1 P36639 1/20 0.56
AOC3 Q16853 1/20 0.56
GPR55 Q9Y2T6 1/20 0.55
GAA P10253 3/20 0.52
POLB P06746 2/20 0.50
IDO1 P14902 1/20 0.50
DDAH1 O94760 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29959355 1.00 ALDH1A1 (0.60) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL12003980 0.98 NPC1 (0.58) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
Hydrochloric Acid SCHEMBL9698101 0.98 ALDH1A1 (0.58) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
Acetonitrile SCHEMBL5634128 0.88 KDM4E (0.48) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL9525450 0.76 KDM4E (0.55) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL30561047 0.75 NPC1 (1.00) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL172216 0.75 NPC1 (1.00) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL30634854 0.75 NPC1 (1.00) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL2878855 0.74 DYRK3 (0.46) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL2878859 0.74 KDM4E (0.54) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3877 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119909545-A Universal repair method for MOF membrane grain boundary defects, MOF membrane repaired by using method, preparation method and gas separation application thereof 天津工业大学 2025-05-02 CN claimed
CN-119505275-B MOF-CGC material and preparation method and application thereof 宁波大学 2025-04-29 CN claimed
US-12263464-B2 Method for in-situ synthesis of metal organic frameworks (MOFs), covalent organic frameworks (COFs) and zeolite imidazolate frameworks (ZIFs), and applications thereof DESICCANT ROTORS INTERNATIONAL PRIVATE LIMITED (IN) 2025-04-01 US claimed
CN-119505275-A MOF-CGC material and preparation method and application thereof 宁波大学 2025-02-25 CN claimed
WO-2023202368-A1 NUCLEIC ACID ENCAPSULATION AND DECAPSULATION METHOD AND NUCLEIC ACID STORAGE MICRO-FLUIDIC CHIP 南方科技大学 2023-10-26 WO claimed
CN-219239914-U Anti-mite antibacterial deodorant moisture-conducting knitted fabric 江苏品创纺织科技有限公司 2023-06-23 CN claimed
CN-114907270-A Preparation method of 2-chlorobenzimidazole 四川德峰药业有限公司 2022-08-16 CN claimed
CN-108473526-B Process for producing oligonucleotide and nucleoside, nucleotide or oligonucleotide 味之素株式会社 2022-08-09 CN claimed
CN-113004206-B Naphthalene derivative fluorescent probe and preparation method and application thereof 齐齐哈尔大学 2022-06-17 CN claimed
CN-112830898-B Lansoprazole impurity for injection and preparation method and application thereof 扬子江药业集团有限公司 2022-03-22 CN claimed
WO-2007007945-A1 PREFLUX COMPOSITION BAIK YANG CHEMICAL CO., LTD. (KR) 2007-01-18 WO claimed
CN-1891393-A Preflux composition BAIK YANG CHEMICAL CO LTD (KR) 2007-01-10 CN claimed
CN-1249037-C Prepn process of 2-chlorobenzimidazole TIANJIN TIANSHILI GROUP CORP L (CN) 2006-04-05 CN claimed
US-20050228006-A1 Process and intermediates for obtaining 1-(1H-benzimidazol-2-YL)-4-(2-aminopyrimidine)piperidine derivatives RAGACTIVES, S.L. 2005-10-13 US claimed
EP-1564212-A1 METHOD AND INTERMEDIA USED TO OBTAIN DERIVATIVES OF 1-(1H- BENZIMIDAZOLE-2-YL)-4-(2-AMINOPYRIMIDINE)PIPERIDINE Ragactives, S.L. (ES) 2005-08-17 EP claimed
CN-1562984-A Compound of hydrosulfuryl-substitution azacycle UNIV ZHEJIANG POLYTECHNIC (CN) 2005-01-12 CN claimed
CN-1486981-A Prepn process of 2-chlorobenzimidazole 天津天士力集团有限公司 2004-04-07 CN claimed
CN-1100780-C Process for preparing 2-chlorobenzimidazole derivatives BAYER AG (DE) 2003-02-05 CN claimed
US-6054589-A Process for preparing 2-chloro-benzimidazole derivatives BAYER AKTIENGESELLSCHAFT (DE) 2000-04-25 US claimed
CN-1206713-A Process for preparing 2-chlorobenzimidazole derivatives BAYER AG (DE) 1999-02-03 CN claimed