SCHEMBL29959355

SCHEMBL29959355

Clc1nc2ccccc2[nH]1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.60
NPC1 O15118 8/20 0.60
RAB9A P51151 8/20 0.60
KDM4E B2RXH2 7/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
NPSR1 Q6W5P4 2/20 0.60
PKM P14618 2/20 0.60
ABCB11 O95342 1/20 0.60
TP53 P04637 1/20 0.60
HSD17B10 Q99714 1/20 0.60
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
MASP2 O00187 1/20 0.56
NUDT1 P36639 1/20 0.56
AOC3 Q16853 1/20 0.56
GPR55 Q9Y2T6 1/20 0.55
GAA P10253 3/20 0.52
POLB P06746 2/20 0.50
IDO1 P14902 1/20 0.50
DDAH1 O94760 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277761 1.00 ALDH1A1 (0.60) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL12003980 0.98 NPC1 (0.58) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
Hydrochloric Acid SCHEMBL9698101 0.98 ALDH1A1 (0.58) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
Acetonitrile SCHEMBL5634128 0.88 KDM4E (0.48) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL9525450 0.76 KDM4E (0.55) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL30561047 0.75 NPC1 (1.00) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL172216 0.75 NPC1 (1.00) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL30634854 0.75 NPC1 (1.00) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL2878855 0.74 DYRK3 (0.46) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL2878859 0.74 KDM4E (0.54) ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250249431-A1 METAL-ORGANIC FRAMEWORK FILM AND METHOD FOR PRODUCING SAME MURATA MANUFACTURING CO., LTD. (JP) 2025-08-07 US disclosed
US-12234398-B2 Metal organic framework (MOF) glass composite comprising metal halide perovskite THE UNIVERSITY OF QUEENSLAND (AU) 2025-02-25 US disclosed
CN-115768761-B Novel benzimidazole derivatives 卡尔那生物科学株式会社 2025-02-25 CN disclosed
CN-119486992-A PI3K alpha inhibitors and methods of use thereof 传达治疗有限公司 2025-02-18 CN disclosed
CN-115836054-B IL4I1 inhibitors and methods of use 默沙东有限责任公司 2024-12-10 CN disclosed
CN-119059967-A Diaryl amine compound with affinity with Tau protein, and preparation method and application thereof 北京师范大学 2024-12-03 CN disclosed
CN-119060050-A Benzimidazole compound and application thereof 中国药科大学 2024-12-03 CN disclosed
US-20240376377-A1 A METAL ORGANIC FRAMEWORK (MOF) GLASS COMPOSITE COMPRISING METAL HALIDE PEROVSKITE THE UNIVERSITY OF QUEENSLAND (AU) 2024-11-14 US disclosed
CN-118645560-A Solar cell and preparation method thereof 广东晟阳华创科技有限公司 2024-09-13 CN disclosed
CN-109311856-B Small molecule modulators of steroid receptor coactivators and methods of use thereof 贝勒医学院 2024-09-06 CN disclosed
WO-2024111176-A1 METAL-ORGANIC FRAMEWORK FILM AND METHOD FOR PRODUCING SAME 株式会社村田製作所 2024-05-30 WO disclosed
CN-112313222-B Tetrahydroisoquinoline derivative, preparation method and application thereof 浙江海正药业股份有限公司 2024-01-26 CN disclosed
CN-115836054-A IL4I1 inhibitors and methods of use 默沙东有限责任公司 2023-03-21 CN disclosed
EP-4146644-A1 IL4I1 INHIBITORS AND METHODS OF USE Merck Sharp & Dohme LLC (US) 2023-03-15 EP disclosed
CN-115768761-A Novel benzimidazole derivatives 卡尔那生物科学株式会社 2023-03-07 CN disclosed
US-20230068539-A1 COMPOSITE FILM FRAMEWORK, AND SENSOR, GAS ADSORPTION FILTER, AND GAS REMOVAL DEVICE USING THE COMPOSITE FILM FRAMEWORK MURATA MANUFACTURING CO., LTD. (JP) 2023-03-02 US disclosed
EP-4097090-A1 BENZIMIDAZOLE DERIVATIVES Merck Patent GmbH (DE) 2022-12-07 EP disclosed
EP-4081295-A1 DIHYDRO-CYCLOPENTA-ISOQUINOLINE SULFONAMIDES DERIVATIVES UCB Biopharma SRL (BE) 2022-11-02 EP disclosed