Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | SQLE | Q14534 | 8/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | ICMT | O60725 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Squalene SCHEMBL28044623 | 0.96 | KMT2A (0.65) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL28439863 | 0.90 | KMT2A (0.63) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| Glycerin SCHEMBL28909257 | 0.87 | FNTA (0.58) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| Squalene SCHEMBL890053 | 0.84 | KMT2A (1.00) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| Squalene SCHEMBL21823197 | 0.84 | KMT2A (1.00) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL23802597 | 0.84 | KMT2A (1.00) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL8013144 | 0.84 | KMT2A (1.00) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| SCHEMBL21639794 | 0.84 | KMT2A (1.00) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| Squalene SCHEMBL8819997 | 0.84 | KMT2A (1.00) | KMT2ASQLEMAPTMEN1CYP3A4 | |
| Squalene SCHEMBL31125292 | 0.84 | KMT2A (1.00) | KMT2ASQLEMAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516325-B | Method for preparing icariside II, cosmetic composition containing the same and the use thereof for skin whitening | AMOREPACIFIC CORP | 2012-03-21 | — | — | CN | disclosed |
| CN-101516325-A | Method for preparing icariside II, cosmetic composition containing the same and the use thereof for skin whitening | AMOREPACIFIC CORP (KR) | 2009-08-26 | — | — | CN | disclosed |