Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.63 |
| ▸ | MEN1 | O00255 | 10/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12717686 | 0.88 | GAA (0.61) | MAPTKMT2AMEN1NPSR1KDM4E | |
| SCHEMBL6721129 | 0.82 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL11913670 | 0.82 | MAPT (0.58) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL27776229 | 0.81 | MAPT (0.58) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL11913677 | 0.81 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL11918184 | 0.81 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL8239298 | 0.81 | KMT2A (0.60) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL8241062 | 0.80 | MAPT (0.56) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL12417173 | 0.80 | MAPT (0.56) | MAPTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL22737807 | 0.79 | MAPT (0.68) | MAPTKMT2AMEN1ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101684115-B | 4-(5-((2-(4-morpholinyl-6-phenylamino group-1,3,5-triazine-2-base) hydrazono) methyl) furan-2-base) benzoic acid, preparing method and application thereof | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2011-12-21 | — | — | CN | disclosed |
| CN-101684115-A | 4-(5-((2-(4-morpholinyl-6-phenylamino group-1,3,5-triazine-2-base) hydrazono) methyl) furan-2-base) benzoic acid, preparing method and application thereof | SHANGHAI INST PHARM INDUSTRY | 2010-03-31 | — | — | CN | disclosed |