Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.60 |
| ▸ | MEN1 | O00255 | 10/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 13/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8241062 | 0.86 | MAPT (0.56) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8232030 | 0.85 | MAPT (0.56) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11918204 | 0.83 | MAPT (0.51) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27776235 | 0.81 | MAPT (0.63) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4410841 | 0.80 | KDM4E (0.69) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11913699 | 0.80 | MAPT (0.55) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11913670 | 0.76 | MAPT (0.58) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6433034 | 0.76 | MEN1 (0.66) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL6433043 | 0.76 | MEN1 (0.66) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL6721129 | 0.75 | MAPT (0.65) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790345-A1 | Triazin beta-secretase inhibitors | Esbatech AG (CH) | 2007-05-30 | — | — | EP | disclosed |
| WO-2007051333-A1 | TRIAZINE BETA-SECRETASE INHIBITORS | ONCALIS AG (CH) | 2007-05-10 | — | — | WO | disclosed |