Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436465 | 0.94 | TNNC1 (0.47) | PPARATNNC1CYP4F2CYP4A11PPARG | |
| SCHEMBL8436682 | 0.93 | TNNC1 (0.49) | PPARATNNC1CYP4F2CYP4A11PPARG | |
| SCHEMBL28801237 | 0.92 | PPARA (0.51) | PPARATNNC1CYP4F2CYP4A11PPARG | |
| SCHEMBL27892640 | 0.91 | PPARA (0.53) | PPARATNNC1PPARGLPLLIPG | |
| Ammonia Solution, Strong SCHEMBL27776481 | 0.89 | CYP4F2 (0.44) | CYP4F2CYP4A11HDAC4MEF2D | |
| SCHEMBL9836116 | 0.88 | PPARA (0.50) | PPARATNNC1PPARGHDAC4MEF2D | |
| SCHEMBL9836110 | 0.88 | PPARA (0.50) | PPARATNNC1PPARGHDAC4MEF2D | |
| SCHEMBL7906722 | 0.87 | HDAC4 (0.47) | PPARATNNC1CYP4F2CYP4A11PPARG | |
| SCHEMBL27875964 | 0.87 | CYP4F2 (0.46) | CYP4F2CYP4A11HDAC4MEF2D | |
| SCHEMBL4172761 | 0.87 | PPARA (0.44) | PPARATNNC1CYP4F2CYP4A11PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101686665-B | Styrenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2014-04-23 | — | — | CN | claimed |
| CN-101686665-A | styrenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2010-03-31 | — | — | CN | claimed |
| CN-101686665-B | Styrenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2014-04-23 | — | — | CN | disclosed |
| CN-101686665-A | styrenyl derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC | 2010-03-31 | — | — | CN | disclosed |