SCHEMBL8436682

SCHEMBL8436682

CCCCCC/C=C/c1cccc(CCc2ccc(CCC)cc2)c1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TNNC1 P63316 1/20 0.49
PPARA Q07869 4/20 0.44
PPARG P37231 1/20 0.42
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39
EPHX2 P34913 1/20 0.39
MAPT P10636 1/20 0.38
ATM Q13315 1/20 0.38
HDAC4 P56524 1/20 0.38
MEF2D Q14814 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8436465 0.99 TNNC1 (0.47) TNNC1PPARAPPARGCYP4F2CYP4A11
SCHEMBL8437030 0.94 PPARA (0.50) TNNC1PPARAPPARGLPLLIPG
Ammonia Solution, Strong SCHEMBL27776409 0.93 PPARA (0.44) TNNC1PPARAPPARGCYP4F2CYP4A11
SCHEMBL27892640 0.90 PPARA (0.53) TNNC1PPARAPPARGLPLLIPG
SCHEMBL8500466 0.89 TNNC1 (0.46) TNNC1PPARAPPARGCYP4F2CYP4A11
SCHEMBL8500468 0.89 TNNC1 (0.46) TNNC1PPARAPPARGCYP4F2CYP4A11
SCHEMBL8438375 0.89 LPL (0.46) TNNC1PPARAPPARGLPLLIPG
SCHEMBL8434921 0.89 LPL (0.46) TNNC1PPARAPPARGLPLLIPG
SCHEMBL8437078 0.89 LPL (0.46) TNNC1PPARAPPARGLPLLIPG
SCHEMBL8433406 0.89 LPL (0.46) TNNC1PPARAPPARGLPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5866035-A LARGE BIREFRINGENCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-02 US disclosed