Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BID | P55957 | 6/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.50 |
| ▸ | BAK1 | Q16611 | 5/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.50 |
| ▸ | EP300 | Q09472 | 2/20 | 0.50 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.50 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4211495 | 1.00 | BID (0.50) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL4211496 | 0.92 | BID (0.58) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL985791 | 0.82 | THRA (0.48) | THRATHRBHSD17B10 | |
| SCHEMBL27914642 | 0.81 | ALDH1A1 (0.54) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL29044856 | 0.81 | PPARA (0.58) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL28709219 | 0.81 | PPARA (0.58) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL28774512 | 0.80 | BID (0.51) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL11511193 | 0.80 | BID (0.54) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL30423156 | 0.80 | BID (0.54) | BIDMCL1BCL2L1BAK1PPARA | |
| SCHEMBL383323 | 0.80 | BID (0.54) | BIDMCL1BCL2L1BAK1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103833693-B | A kind of taxol compound and the pharmaceutical composition containing this taxol compound | YUEKANG PHARMACEUTICAL GROUP CO., LTD. (CN) | 2016-02-24 | — | — | CN | disclosed |
| CN-103006539-B | A kind of polymeric micelle medicine composition and preparation method thereof | SHENYANG PHARMACEUTICAL UNIVERSITY (CN) | 2015-12-23 | — | — | CN | disclosed |
| CN-102357077-B | Protein nanometer particle for wrapping slightly soluble medicines and preparation method thereof | UNIV CHINA PHARMA | 2014-06-11 | — | — | CN | disclosed |
| CN-102357076-B | Preparation method of protein nanoparticles coating insoluble drug | UNIV CHINA PHARMA | 2014-06-11 | — | — | CN | disclosed |
| CN-103833693-A | Taxol compound and medicine composition containing same | YOUCARE PHARMACEUTICAL GROUP | 2014-06-04 | — | — | CN | disclosed |
| CN-102327230-B | Protein nanometer granules wrapped with taxane medicaments and preparation method for nanometer granules | UNIV CHINA PHARMA | 2014-05-21 | — | — | CN | disclosed |
| CN-102579338-B | Preparation method and application of paclitaxel intravenous fat emulsion | UNIV CAPITAL MEDICAL | 2013-06-19 | — | — | CN | disclosed |
| CN-102166190-B | Paclitaxel nano liposomes of dual targeting tumor and method for preparing paclitaxel nano liposomes | SHANGHAI PULMONARY HOSPITAL | 2013-04-10 | — | — | CN | disclosed |
| CN-102389399-B | Preparation method of drug-loaded microspheres capable of enhancing anticancer effect of paclitaxel by ultraviolet radiation and application thereof | UNIV SOUTHEAST | 2013-04-03 | — | — | CN | disclosed |
| CN-103006539-A | Polymeric micelle medicine composition and preparation method thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-04-03 | — | — | CN | disclosed |
| CN-101831005-B | PH sensitive type chitosan derivant and application thereof in pharmaceutics | UNIV CHINA PHARMA | 2012-08-15 | — | — | CN | disclosed |
| CN-102579338-A | Preparation method and application of paclitaxel intravenous fat emulsion | UNIV CAPITAL MEDICAL | 2012-07-18 | — | — | CN | disclosed |
| CN-102389399-A | Preparation method of drug-loaded microspheres capable of enhancing anticancer effect of paclitaxel by ultraviolet radiation and application thereof | UNIV SOUTHEAST | 2012-03-28 | — | — | CN | disclosed |
| CN-102357077-A | Protein nanometer particle for wrapping slightly soluble medicines and preparation method thereof | UNIV CHINA PHARMA | 2012-02-22 | — | — | CN | disclosed |
| CN-102357076-A | Preparation method of protein nanoparticles coating insoluble drug | UNIV CHINA PHARMA | 2012-02-22 | — | — | CN | disclosed |
| CN-102327230-A | Protein nanometer granules wrapped with taxane medicaments and preparation method for nanometer granules | UNIV CHINA PHARMA | 2012-01-25 | — | — | CN | disclosed |
| CN-101658516-B | Taxol medicinal compositions and preparation method thereof | QILU PHARMACEUTICAL CO LTD | 2011-10-05 | — | — | CN | disclosed |
| CN-102166190-A | Paclitaxel nano liposomes of dual targeting tumor and method for preparing paclitaxel nano liposomes | SHANGHAI PULMONARY HOSPITAL | 2011-08-31 | — | — | CN | disclosed |
| CN-101831005-A | PH sensitive type chitosan derivant and application thereof in pharmaceutics | UNIV CHINA PHARMA | 2010-09-15 | — | — | CN | disclosed |
| CN-101658516-A | Taxol medicinal compositions and preparation method thereof | QILU PHARMACEUTICAL CO LTD | 2010-03-03 | — | — | CN | disclosed |