Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27603813 | 0.89 | HDAC6 (0.41) | HDAC6HDAC1HDAC2ALDH1A1CA14 | |
| SCHEMBL27844192 | 0.84 | HDAC6 (0.41) | HDAC6HDAC1HDAC2KDM6BKDM5C | |
| SCHEMBL245883 | 0.84 | PHF8 (0.55) | HDAC6HDAC1HDAC2KDM6BKDM5C | |
| SCHEMBL14715022 | 0.78 | HDAC6 (0.38) | HDAC6HDAC1HDAC2CA14CA12 | |
| SCHEMBL10446 | 0.75 | ALDH1A1 (0.55) | HDAC6HDAC1HDAC2ALDH1A1CA14 | |
| SCHEMBL23541555 | 0.74 | HDAC6 (0.38) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL6391230 | 0.74 | HDAC6 (0.38) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL13778771 | 0.74 | HDAC6 (0.50) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL28153358 | 0.74 | CA14 (0.44) | HDAC6HDAC1HDAC2ALDH1A1CA14 | |
| SCHEMBL11765115 | 0.73 | ALDH1A1 (0.52) | HDAC6HDAC1HDAC2ALDH1A1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867648-A | Extension of chemical substrates for genetic code reprogramming to include long chain carbons and cyclic amino acids | 西北大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-101677540-A | Herbicidally effective composition | EIKE HUPE | 2010-03-24 | — | — | CN | disclosed |