Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27776657 | 0.89 | CNR2 (0.35) | CNR2LMNAPOLBCRHBPCRHR2 | |
| SCHEMBL27776670 | 0.84 | LMNA (0.37) | LMNAMAPTALDH1A1SMN1; SMN2AURKA | |
| SCHEMBL841732 | 0.79 | CNR2 (0.54) | CNR2CNR1ALDH1A1SMN1; SMN2GSTO1 | |
| SCHEMBL27797574 | 0.77 | F10 (0.34) | LMNAMAPTALDH1A1SMN1; SMN2F2 | |
| SCHEMBL27797954 | 0.76 | LMNA (0.32) | LMNAIDH1ALDH1A1 | |
| SCHEMBL27797641 | 0.72 | LMNA (0.36) | LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27797878 | 0.72 | CYP3A4 (0.32) | CNR2 | |
| SCHEMBL27835248 | 0.70 | LMNA (0.37) | CNR2LMNAPOLBCRHBPCRHR2 | |
| SCHEMBL27572409 | 0.67 | CHRM2 (0.36) | CNR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27693489 | 0.66 | POLB (0.36) | LMNAPOLBPIK3R1PIK3CAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687797-A | Malonamide derivatives with antithrombotic activity | SANOFI AVENTIS | 2010-03-31 | — | — | CN | disclosed |