Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27776670 | 0.88 | LMNA (0.37) | LMNAALDH1A1SMN1; SMN2P2RX7MAPT | |
| SCHEMBL27776657 | 0.84 | CNR2 (0.35) | LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27776669 | 0.80 | F10 (0.33) | LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27776830 | 0.72 | CNR2 (0.36) | LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27835248 | 0.69 | LMNA (0.37) | LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL27745075 | 0.69 | CA1 (0.43) | LMNAALDH1A1SMN1; SMN2P2RX7MAPT | |
| SCHEMBL27797639 | 0.68 | ERN1 (0.52) | ALDH1A1MAPTKDM4E | |
| SCHEMBL27735019 | 0.67 | PKM (0.45) | LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL27693489 | 0.65 | POLB (0.36) | LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL840281 | 0.65 | ALDH1A1 (0.49) | LMNAALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687797-A | Malonamide derivatives with antithrombotic activity | SANOFI AVENTIS | 2010-03-31 | — | — | CN | disclosed |