Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPD | P32754 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27756390 | 0.91 | P2RY12 (0.53) | P2RY12KDM4ETP53ALDH1A1HPGD | |
| SCHEMBL1639567 | 0.88 | P2RY12 (0.49) | P2RY12KDM4ETP53SMN1; SMN2LMNA | |
| SCHEMBL1639033 | 0.79 | P2RY12 (0.48) | P2RY12KDM4ETP53ALDH1A1HPGD | |
| SCHEMBL15494798 | 0.78 | P2RY12 (0.64) | P2RY12KDM4ETP53ALDH1A1HPGD | |
| SCHEMBL12727376 | 0.78 | P2RY12 (0.56) | P2RY12KDM4ETP53ALDH1A1HPGD | |
| SCHEMBL1640201 | 0.78 | P2RY12 (0.68) | P2RY12KDM4ETP53ALDH1A1HPGD | |
| SCHEMBL27756396 | 0.77 | P2RY12 (0.59) | P2RY12KDM4ETP53ALDH1A1HPGD | |
| SCHEMBL3838454 | 0.77 | P2RY12 (0.54) | P2RY12KDM4ETP53ALDH1A1HPGD | |
| SCHEMBL1640891 | 0.76 | P2RY12 (0.57) | P2RY12KDM4ETP53ALDH1A1HPGD | |
| SCHEMBL14525281 | 0.75 | ALDH1A1 (0.58) | P2RY12KDM4ETP53ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101534832-A | Substituted nitrogen containing heterocycles as platelet ADP receptor inhibitors | PORTOLA PHARM INC (US) | 2009-09-16 | — | — | CN | claimed |
| CN-101534832-A | Substituted nitrogen containing heterocycles as platelet ADP receptor inhibitors | PORTOLA PHARM INC (US) | 2009-09-16 | — | — | CN | disclosed |